There’s limited research into the safety of using melatonin supplements during pregnancy. Birth control pills may increase the risk of side effects from melatonin.īecause melatonin supplements can make you tired and drowsy, avoid mixing them with:Īre there any people who should avoid taking melatonin? Blood pressure may get worse when melatonin is taken with these medications. Melatonin use can affect blood sugar levels. Melatonin can potentially interfere with immunosuppressive drugs. Melatonin may make these medications less effective.
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